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Table 4 False recent seroconverters and protective effect of MC on HIV incidence as calculated using BED and AI in combination

From: Can HIV incidence testing be used for evaluating HIV intervention programs? A reanalysis of the Orange Farm male circumcision trial (ANRS-1265)

BED-AI

      

BED - AI Cut-off

0.325 - 31.6

0.733 - 80.5

0.900 - 90.0

1.51 - 94.0

1.89 - 96.0

NC

Window period

65.9d

159d

213d

268d

300d

NC

False LTS (%)

NC

1/9 (11)

1/13 (7.7)

2/16 (13)

3/27 (11)

NC

95% CI

 

1 to 40

0.4 to 30

2 to 33

3 to 26

 

Observed false RS (%)

0/124 (0)

2/124 (1.6)

2/124 (1.6)

6/124 (4.8)

NC

NC

95% CI

0 to 2.4

0.25 to 5.0

0.3 to 5

1.9 to 9.6

  

1Calculated false RS (%)

0.9

2.1

2.7

3.5

3.9

NC

Tested RSs

     

NC

Intervention - Control

2 - 7

8 - 17

9-21

11 - 30

16 - 41

 

Uncorrected effect (%)

73

55

59

65

63

NC

95% CI

NC

-1 to 84

8 to 84

33 to 85

36 to 81

 

2Correction

     

NC

Intervention (%)

36

21

24

25

20

 

Control (%)

15

14

15

13

11

 

Total (%)

19

16

17

17

13

 

Corrected effect (%)

80

59

64

70

67

NC

95% CI

NC

-2 to 93

6 to 92

39 to 90

38 to 86

 
  1. See table caption of Table 3