Table 3 Categorical variables associated with the severity of the disease in nephropathia epidemica patients, divided into four groups according to maximum plasma interleukin-6 and C-reactive protein levels.
Group 1 (N = 37) CRP ≤ 69 mg/l IL-6 ≤ 14.05 pg/ml | Group 2 (N = 22) CRP > 69 mg/l IL-6 ≤ 14.05 pg/ml | Group 3 (N = 23) CRP ≤ 69 mg/l IL-6 > 14.05 pg/ml | Group 4 (N = 36) CRP > 69 mg/l IL-6 > 14.05 pg/ml | P-value | |
|---|---|---|---|---|---|
Gender (males) | 28 (76%) | 14 (64%) | 16 (70%) | 28 (78%) | 0.645 |
Shock | 0 (0%) | 0 (0%) | 1 (4%) | 2 (6%) | |
Dialysis treatment | 1 (3%) | 0 (0%) | 2 (9%) | 3 (8%) | |
Pathologic chest x-ray | 6 (23%) | 4 (25%) | 6 (30%) | 14 (42%) | 0.390 |
Hospital stay > 7 days | 7 (19%) | 5 (23%) | 11 (48%) | 19 (53%) | 0.007 |
Creatinine max > 193 μmol/l | 18 (49%) | 5 (23%) | 16 (70%) | 19 (53%) | 0.017 |
Platelets min ≤ 66 × 109/l | 14 (38%) | 7 (32%) | 13 (57%) | 27 (75%) | 0.002 |