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Table 1 General characteristics and changes for subjects with undetectable HIV replication

From: Human immunodeficiency virus type I-specific CD8+T cell subset abnormalities in chronic infection persist through effective antiretroviral therapy

ID Duration of infection aVL zenith bCD4 nadir cDuration of suppression dCD4i CD4f eMonths study course fCD8+ IFNγ+ CD45RA+ i CD8+ IFNγ+ CD45RA+ f
27 >15 yrs 5.13 308 21 months 702 1364 90 13% 26%
30 >15 yrs 4.53 314 84 months 630 1089 28 ND ND
50 >15 yrs 5.45 18 7 months 220 627 108 52% 50%
62 >15 yrs 4.61 154 32 months 738 756 28 10% 15%
90 >15 yrs 6.22 73 24 months 280 352 96 79% 84%
109 >15 yrs 3.66 145 72 months 740 665 24 22% 16%
128 >12 yrs 4.53 364 3 months 570 912 66 44% 52%
134 >12 yrs 5.01 96 72 months 850 1020 24 ND ND
143 >10 yrs 4.77 400 24 months 400 682 60 ND 22%
149 >9 yrs 5.67 9 36 months 338 264 24 ND ND
155 >9 yrs 5.10 210 3 months 368 408 54 10% 10%
174 >7 yrs 5.53 380 12 months 494 768 30 ND ND
176 >7 yrs <2.6 245 12 months 361 750 36 ND ND
193 >6 yrs <2.6 40 12 months 405 324 24 23% 13%
200 >5 yrs >5.88 192 3 months 567 957 24 ND ND
  1. aThe highest recorded virus load (VL) for each subject in log10 copies HIV RNA/mL plasma.
  2. bThe lowest recorded peripheral blood CD4+ T lymphocyte count for each subject.
  3. cThe length of time before analysis of HIV-specific CD8+ T cell responses for which each subject experienced suppression of viremia below detectable levels.
  4. dThe number of CD4+ T lymphocytes/μL peripheral blood for each subject at beginning (CD4i) and end (CD4f) of period over which HIV-specific CD8+ T cell responses were assessed.
  5. eTotal time period over which four assessments of HIV-specific CD8+ T cell responses occurred.
  6. fPercentage of HIV-specific CD8+ T cells producing INF-γ that expressed CD45RA at beginning (i) and end (f) of period over which HIV-specific CD8+ T cell responses were assessed.