Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: A Danish historical cohort study

Table 3 Comparison of outcomes for CAL and HAL.

	CAL	HAL^a
Variables	No. (%)	No. (%)	p-value^b
Admission to intensive care unit	116 (42.6)	37 (61.7)	0.008*
Days in intensive care, median days (IQR)	12 (5-20)	10 (6-23)	0.79
Mechanical ventilation	93 (34.2)	32 (53.3)	0.06
Hemodialysis	43 (15.8)	18 (30.0)	0.01*
Inotropic support	86 (31.6)	29 (48.3)	0.02*
Medical complications
Disseminated intravascular coagulation	9 (3.3)	3 (5.0)	0.53
Rhabdomyolysis	4 (1.5)	1 (1.7)	0.92
Myocardial infarction	5 (1.8)	4 (6.7)	0.04*
Cerebrovascular insult	5 (1.8)	0 (0)	0.29
Outcome
30-day mortality^c	35 (12.9)	20 (33.3)	x
90-day mortality^c	43 (15.8)	33 (55.0)	x

a A case was defined as hospital-acquired if the patient had been admitted within the preceding 10 days or if the patient developed
symptoms of legionellosis more than 2 days after hospital admission.
b Differences between the groups were analyzed with χ² or Fisher's exact test as appropriate for categorical variables.
Continuous variables were compared using two-sample t-test (normal distribution) or Mann-Whitney U-test (non-normal distribution).
c For community-acquired cases time from admission. For hospital-acquired cases time from beginning of symptoms.
No comparison between groups for these variables since baseline was defined in different ways.
* P-level < 0.05 is considered statistically significant.
IQR: Interquartile range.

ISSN: 1471-2334