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Table 1 Performance characteristics of the GenoType® MTBDRplus assay.

From: Validation of the GenoType® MTBDRplus assay for detection of MDR-TB in a public health laboratory in Thailand

A. Performance characteristics of the GenoType® MTBDRplusassay for the detection of RIF- and INH-resistance in comparison to drug-susceptibility test results using the MGIT BACTEC 960.
   INH Resistance RIF Resistance
   MGIT AST Result MGIT AST Result
Specimen Type GenoType® MTBDR plus Result + - Sensitivity
(%)
Specificity (%) + - Sensitivity (%) Specificity (%)
AFB+ Sputum + (Resistant) 27 0 93.1 100 19 0 100 100
  - (Sensitive) 2 135    0 145   
Stored Isolate + 14 0 100 100 6 0 100 100
  - 0 36    0 44   
All Specimens + 41 0 95.3 100 25 0 100 100
  - 2 171    0 189   
B. Performance characteristics of the GenoType ® MTBDR plus assay for the detection of MDR-TB in comparison to drug-susceptibility test results using the MGIT BACTEC 960.
  MDR-TB
MGIT AST Result
        
Specimen Type GenoType ® MTBDR plus Result + - Sensitivity
(%)
Specificity (%)     
AFB+ Sputum + (Resistant) 12 0 92.3 100     
  - (Sensitive) 1 151       
Stored Isolate + 5 0 100 100     
  - 0 45       
All Specimens + 17 0 94.4 100     
  - 1 196       
  1. + = Resistant; - = Sensitive