Table 2 Demographic, clinical characteristics and laboratory findings on admission of the 208 scrub typhus patients
From: Clinical and laboratory findings associated with severe scrub typhus
Characteristics | Severe scrub typhus (n = 89) | Non-severe scrub typhus (n = 119) |
|---|---|---|
Demographic data | ||
Age, mean years ± SD* | 68.56 ± 11.1 | 57.32 ± 15.7 |
Gender, no. of male/no. of female (% of male) | 28/61(31.5) | 43/76(36.1) |
Duration of illness before admission, days | 8.13 ± 5.4 | 6.95 ± 3.7 |
Length of hospitalization, mean days ± SD* | 11.5 ± 9.6 | 7.21 ± 2.8 |
Mean duration from disease onset to effective antibiotic therapy (days) | 8.34 ± 5.1 | 7.11 ± 3.7 |
Underlying diseases (Diabetes, Liver cirrhosis, COPD) | 6(6.8%) | 4(3.3%) |
Clinical symptoms and signs | ||
Headache, no. (%) of patients | 74 (83.1) | 109 (91.6) |
Myalgia, no. (%) of patients | 66 (74.2) | 95(79.8) |
Skin rash, no. (%) of patients | 78(87.6) | 111 (93.3) |
Eschar, no.(%) of patients* | 77 (86.5) | 117 (98.3) |
Laboratory values | ||
WBC count (no. of cells × 1, 000/mm3) * | 9.4 ± 4.3 | 6.6 ± 3.1 |
Hemoglobin (g/dL) * | 12.0 ± 1.8 | 12.7 ± 1.3 |
Platelet count (no. of cells × 1, 000/mm3) | 149.31 ± 77.3 | 153.7 ± 72.9 |
AST (IU/L) | 100.9 ± 70.0 | 104.1 ± 86.8 |
ALT (IU/L) | 75.0 ± 74.4 | 91.2 ± 86.5 |
ALP (U/L) | 136.4 ± 120.0 | 118.5 ± 87.1 |
Bilirubin (mg/dL) | 1.0 ± 1.0 | 0.8 ± 0.6 |
Albumin (g/dL) * | 3.3 ± 0.6 | 3.8 ± 0.5 |
LDH (U/L) | 818.5 ± 240.1 | 874.3 ± 264.2 |
CPK (U/L) | 232.3 ± 609.5 | 263.5 ± 698.5 |
ADA (IU/L) | 83.6 ± 24.9 | 79.6 ± 24.7 |
Serum creatinine (mg/dL) * | 1.5 ± 0.9 | 1.0 ± 0.2 |
Fibrinogen (mg/dL) * | 309.2 ± 97.4 | 348.2 ± 90.4 |
CRP (mg/dL) * | 10.5 ± 5.0 | 8.1 ± 5.6 |
ESR (mm/hr) | 19.4 ± 17.7 | 7.0 ± 15.0 |
PT (sec) | 12.2 ± 1.0 | 12.3 ± 1.3 |
aPTT (sec) * | 32.6 ± 5.8 | 30.5 ± 4.6 |