Cellular immunity in children with successful immunoprophylactic treatment for mother-to-child transmission of hepatitis B virus

Table 2 Patient characteristics, IFN-γe nzyme-linked immunosorbent spot, and serum HBV DNA levels of hepatitis B surface antigen-positive children and their mothers.

Patient ID*	Age (years)	Gender	Levels of serum ALT (IU/L)	Hepatitis B e antigen status	† core 117-125 (Spots/10⁶ PBMCs)	† pol 756-764 (Spots/10⁶ PBMCs)	Levels of serum hepatitis B virus DNA (copies/mL)
M9	33		18	Pos	12.6	53.9	>10^8.8
C9	3	Male	33	Pos	12.8	5.7	10^8.2
M10	47		21	Pos	12.8	30.8	10^8.3
C10	22	Female	30	Pos	20.7	26.2	10^8.6
M11	32		17	Pos	22.5	48.4	10^8.6
C11	4	Female	16	Pos	7.0	5.3	10^8.7

* M and C indicate mother and child, respectively. Number indicates family ID. † More than 50 spots/10⁶ PBMCs were defined as a significant HBV-specific T-cell response. PBMCs, peripheral blood mononuclear cells. Pos, positive Neg, negative

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