Viral diseases

Section edited by Jodie McVernon and Julian Tang

This section aims to publish studies looking at all aspects of of the prevention, diagnosis and management of viral diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. HIV, HIV-associated infections and sexually transmitted diseases are considered in separate sections.

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  1. Research article

    An assessment of the geographical risks of wild and vaccine-derived poliomyelitis outbreaks in Africa and Asia

    The international spread of wild poliomyelitis outbreaks continues to threaten eradication of poliomyelitis and in 2014 a public health emergency of international concern was declared. Here we describe a risk ...

    Kathleen M. O’Reilly, Christine Lamoureux, Natalie A. Molodecky, Hil Lyons, Nicholas C. Grassly and Graham Tallis

    BMC Infectious Diseases 2017 17:367

    Published on: 26 May 2017

  2. Research article

    Varicella-zoster virus seroprevalence in children and adolescents in the pre-varicella vaccine era, Germany

    In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the pre-var...

    Miriam Wiese-Posselt, Anette Siedler, Annette Mankertz, Andreas Sauerbrei, Hartmut Hengel, Ole Wichmann and Christina Poethko-Müller

    BMC Infectious Diseases 2017 17:356

    Published on: 19 May 2017

  3. Research article

    Estimation of the burden of varicella in Europe before the introduction of universal childhood immunization

    Varicella is generally considered a mild disease. Disease burden is not well known and country-level estimation is challenging. As varicella disease is not notifiable, notification criteria and rates vary betw...

    Margarita Riera-Montes, Kaatje Bollaerts, Ulrich Heininger, Niel Hens, Giovanni Gabutti, Angel Gil, Bayad Nozad, Grazina Mirinaviciute, Elmira Flem, Audrey Souverain, Thomas Verstraeten and Susanne Hartwig

    BMC Infectious Diseases 2017 17:353

    Published on: 18 May 2017

  4. Research article

    Reemergence of yellow fever in Ethiopia after 50 years, 2013: epidemiological and entomological investigations

    Yellow Fever (YF) is a viral hemorrhagic disease transmitted by aedes mosquito species. Approximately, 200,000 cases and 30,000 deaths occur worldwide every year. In Ethiopia, the last outbreak was reported in 19...

    Abrham Lilay, Negga Asamene, Abyot Bekele, Mesfin Mengesha, Milliyon Wendabeku, Israel Tareke, Abiy Girmay, Yonas Wuletaw, Abate Adossa, Yamar Ba, Amadou Sall, Daddi Jima and Debritu Mengesha

    BMC Infectious Diseases 2017 17:343

    Published on: 15 May 2017

  5. Research article

    Incidence and comparison of retrospective and prospective data on respiratory and gastrointestinal infections in German households

    Acute respiratory infections (ARI) and acute gastrointestinal infections (AGI) are the most common childhood infections, and corresponding data can either be collected prospectively or retrospectively. The aim...

    Kristin Maria Schlinkmann, Abhishek Bakuli and Rafael Mikolajczyk

    BMC Infectious Diseases 2017 17:336

    Published on: 11 May 2017

  6. Research article

    Relative incidence and individual-level severity of seasonal influenza A H3N2 compared with 2009 pandemic H1N1

    Two subtypes of influenza A currently circulate in humans: seasonal H3N2 (sH3N2, emerged in 1968) and pandemic H1N1 (pH1N1, emerged in 2009). While the epidemiological characteristics of the initial wave of pH...

    Kin On Kwok, Steven Riley, Ranawaka A. P. M. Perera, Vivian W. I. Wei, Peng Wu, Lan Wei, Daniel K. W. Chu, Ian G. Barr, J. S. Malik Peiris and Benjamin J. Cowling

    BMC Infectious Diseases 2017 17:337

    Published on: 11 May 2017

  7. Research article

    A case control study on family history as a risk factor for herpes zoster and associated outcomes, Beijing, China

    Hospital-based case control studies have found family history of herpes zoster (HZ) was associated with risk of HZ, but the role of family history is not fully examined for other HZ-associated outcomes such as...

    Luodan Suo, Li Lu, Juan Li, Mu Sun, Haihong Wang, Xinhui Peng, Fan Yang, Xinghuo Pang, Mona Marin and Chengbin Wang

    BMC Infectious Diseases 2017 17:334

    Published on: 9 May 2017

  8. Research article

    Epidemiological and molecular characteristics of emergent dengue virus in Yunnan Province near the China-Myanmar-Laos border, 2013–2015

    Yunnan Province is located in southwestern China and neighbors the Southeast Asian countries, all of which are dengue-endemic areas. In 2000–2013, sporadic imported cases of dengue fever (DF) were reported alm...

    Ting-Song Hu, Hai-Lin Zhang, Yun Feng, Jian-Hua Fan, Tian Tang, Yong-Hua Liu, Liu Zhang, Xiao-Xiong Yin, Gang Chen, Hua-Chang Li, Jin Zu, Hong-Bin Li, Yuan-Yuan Li, Jing Yu, Fu-Qiang Zhang and Quan-Shui Fan

    BMC Infectious Diseases 2017 17:331

    Published on: 8 May 2017

  9. Research article

    Using electronic health records and Internet search information for accurate influenza forecasting

    Accurate influenza activity forecasting helps public health officials prepare and allocate resources for unusual influenza activity. Traditional flu surveillance systems, such as the Centers for Disease Contro...

    Shihao Yang, Mauricio Santillana, John S. Brownstein, Josh Gray, Stewart Richardson and S. C. Kou

    BMC Infectious Diseases 2017 17:332

    Published on: 8 May 2017

  10. Research article

    Valine/isoleucine variants drive selective pressure in the VP1 sequence of EV-A71 enteroviruses

    In 2011–2012, Northern Vietnam experienced its first large scale hand foot and mouth disease (HFMD) epidemic. In 2011, a major HFMD epidemic was also reported in South Vietnam with fatal cases. This 2011–2012 ...

    Nghia Ngu Duy, Le Thi Thanh Huong, Patrice Ravel, Le Thi Song Huong, Ankit Dwivedi, October Michael Sessions, Yan’An Hou, Robert Chua, Guilhem Kister, Aneta Afelt, Catherine Moulia, Duane J. Gubler, Vu Dinh Thiem, Nguyen Thi Hien Thanh, Christian Devaux, Tran Nhu Duong…

    BMC Infectious Diseases 2017 17:333

    Published on: 8 May 2017

  11. Research article

    Assessing real-time Zika risk in the United States

    Confirmed local transmission of Zika Virus (ZIKV) in Texas and Florida have heightened the need for early and accurate indicators of self-sustaining transmission in high risk areas across the southern United S...

    Lauren A. Castro, Spencer J. Fox, Xi Chen, Kai Liu, Steven E. Bellan, Nedialko B. Dimitrov, Alison P. Galvani and Lauren Ancel Meyers

    BMC Infectious Diseases 2017 17:284

    Published on: 4 May 2017

  12. Technical advance

    Fluorescence in situ hybridization is superior for monitoring Epstein Barr viral load in infectious mononucleosis patients

    Epstein Barr virus (EBV) plays a causal role in some diseases, including infectious mononucleosis, lymphoproliferative diseases and nasopharyngeal carcinoma. Detection of EBV infection has been shown to be a u...

    Pengfei Cao, Meili Zhang, Wei Wang, Yafei Dai, Buqing Sai, Jun Sun, Lujuan Wang, Fan Wang, Guiyuan Li and Juanjuan Xiang

    BMC Infectious Diseases 2017 17:323

    Published on: 3 May 2017

  13. Research article

    Differential host gene responses from infection with neurovirulent and partially-neurovirulent strains of Venezuelan equine encephalitis virus

    Venezuelan equine encephalitis virus (VEEV) is an alphavirus in the family Togaviridae. VEEV causes a bi-phasic illness in mice where primary replication in lymphoid organs is followed by entry into the central n...

    Paridhi Gupta, Anuj Sharma, Jing Han, Amy Yang, Manish Bhomia, Barbara Knollmann-Ritschel, Raj K Puri and Radha K Maheshwari

    BMC Infectious Diseases 2017 17:309

    Published on: 26 April 2017

  14. Case report

    Lessons learned by surveillance during the tail-end of the Ebola outbreak in Guinea, June-October 2015: a case series

    By the end of the 2013–2016 West African Ebola Virus Disease (EVD) outbreaks, a total of 3814 cases (probable and confirmed) and 2544 deaths were reported in Guinea. Clearly, surveillance activities aiming at ...

    Mory Keïta, Fatoumata Conté, Boubacar Diallo, Dieudonné Lufwa, Jacques Katomba, René Snacken, Raymond Pallawo, Aminata Tolno, Amadou Bailo Diallo, Mamadou Harouna Djingarey and Lorenzo Subissi

    BMC Infectious Diseases 2017 17:304

    Published on: 24 April 2017

  15. Research article

    Viral aetiologies of acute encephalitis in a hospital-based South Asian population

    The aetiological spectrum of acute encephalitis shows inter- and intra-geographical variations. We aimed to identify the viruses that cause infectious encephalitis in Sri Lanka, which represents a South Asian ...

    Janarthani Lohitharajah, Neelika Malavige, Carukshi Arambepola, Jithangi Wanigasinghe, Ranjanie Gamage, Padma Gunaratne, Pyara Ratnayake and Thashi Chang

    BMC Infectious Diseases 2017 17:303

    Published on: 24 April 2017

  16. Research article

    Point of sampling detection of Zika virus within a multiplexed kit capable of detecting dengue and chikungunya

    Zika, dengue, and chikungunya are three mosquito-borne viruses having overlapping transmission vectors. They cause diseases having similar symptoms in human patients, but requiring different immediate manageme...

    Ozlem Yaren, Barry W. Alto, Priyanka V. Gangodkar, Shatakshi R. Ranade, Kunal N. Patil, Kevin M. Bradley, Zunyi Yang, Nikhil Phadke and Steven A. Benner

    BMC Infectious Diseases 2017 17:293

    Published on: 20 April 2017

  17. Research article

    Rubella Seroprevalence and real-time PCR detection of RUBV among Congolese pregnant women

    Rubella is an acute infectious disease caused by Rubella virus (RUBV). RUBV remains an important pathogen worldwide, causing approximately 100 000 cases of congenital rubella syndrome (CRS) every year; and the...

    Josue Zanga, Makola Kennedy Mbanzulu, Arnold-Freddy Kabasele, Nlandu Roger Ngatu and Dimosi Roger Wumba

    BMC Infectious Diseases 2017 17:250

    Published on: 5 April 2017

  18. Research article

    Spatial, temporal and spatio-temporal clusters of measles incidence at the county level in Guangxi, China during 2004–2014: flexibly shaped scan statistics

    Outbreaks of measles re-emerged in Guangxi province during 2013–2014, where measles again became a major public health concern. A better understanding of the patterns of measles cases would help in identifying...

    Xianyan Tang, Alan Geater, Edward McNeil, Qiuyun Deng, Aihu Dong and Ge Zhong

    BMC Infectious Diseases 2017 17:243

    Published on: 4 April 2017

  19. Research article

    Upper airway viruses and bacteria in urban Aboriginal and Torres Strait Islander children in Brisbane, Australia: a cross-sectional study

    Respiratory morbidity in Australian Indigenous children is higher than their non-Indigenous counterparts, irrespective of urban or remote residence. There are limited studies addressing acute respiratory illne...

    Kerry-Ann F. O’Grady, Kerry K. Hall, Theo P. Sloots, Jennie Anderson and Anne B. Chang

    BMC Infectious Diseases 2017 17:245

    Published on: 4 April 2017

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