HIV and co-infections

Section edited by Carlo Torti and Andrea De Luca

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of HIV and HIV-associated infections in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section also aims to publish studies on the adverse events of HAART and non HIV-related comorbidities in the HAART era.

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  1. Research article

    The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study

    Levels of non-neutralising antibodies (AB) to the C5 domain of HIV Env gp120 are inversely related to progression of HIV infection. In this phase I/II clinical study we investigated safety of Vacc-C5, a peptid...

    Kristin Brekke, Maja Sommerfelt, Mats Ökvist, Anne Margarita Dyrhol-Riise and Dag Kvale

    BMC Infectious Diseases 2017 17:228

    Published on: 24 March 2017

  2. Research article

    Cytomegalovirus infection in HIV-infected versus non-infected infants and HIV disease progression in Cytomegalovirus infected versus non infected infants early treated with cART in the ANRS 12140—Pediacam study in Cameroon

    The outcome of CMV/HIV co-infection in infants treated early with combined antiretroviral therapy (cART) in resource-limited settings has not been described.

    Anfumbom K. W. Kfutwah, Paul Alain T. Ngoupo, Casimir Ledoux Sofeu, Francis Ateba Ndongo, Georgette Guemkam, Suzie Tetang Ndiang, Félicité Owona, Ida Calixte Penda, Patrice Tchendjou, Christine Rouzioux, Josiane Warszawski, Albert Faye and Mathurin Cyrille Tejiokem

    BMC Infectious Diseases 2017 17:224

    Published on: 23 March 2017

  3. Research article

    Lamivudine/dolutegravir dual therapy in HIV-infected, virologically suppressed patients

    Little is known about the applicability of dual treatments based on integrase inhibitors. We explored the combination of lamivudine + dolutegravir as an option when switching from standard cART in virologicall...

    Franco Maggiolo, Roberto Gulminetti, Layla Pagnucco, Margherita Digaetano, Simone Benatti, Daniela Valenti, Annapaola Callegaro, Diego Ripamonti and Cristina Mussini

    BMC Infectious Diseases 2017 17:215

    Published on: 16 March 2017

  4. Research article

    Role of systemic inflammation scores for prediction of clinical outcomes in patients treated with atazanavir not boosted by ritonavir in the Italian MASTER cohort

    Atazanavir (ATV) not boosted by ritonavir (uATV) has been frequently used in the past for switching combination antiretroviral therapy (cART). However, the clinical outcomes and predictors of such strategy are...

    Maria Concetta Postorino, Mattia Prosperi, Emanuele Focà, Eugenia Quiros-Roldan, Elisa Di Filippo, Franco Maggiolo, Alberto Borghetti, Nicoletta Ladisa, Massimo Di Pietro, Andrea Gori, Laura Sighinolfi, Angelo Pan, Nicola Mazzini and Carlo Torti

    BMC Infectious Diseases 2017 17:212

    Published on: 15 March 2017

  5. Research article

    Elevated prevalence of multidrug-resistant gram-negative organisms in HIV positive men

    Routes of transmission of multidrug-resistant gram-negative organisms (MDRGN) are not completely understood. Since sexual transmission of MDRGN might represent a potential mode that has not been noticed so far...

    Claudia Reinheimer, Oliver T. Keppler, Christoph Stephan, Thomas A. Wichelhaus, Imke Friedrichs and Volkhard A. J. Kempf

    BMC Infectious Diseases 2017 17:206

    Published on: 13 March 2017

  6. Research article

    Systemic inflammation-based scores and mortality for all causes in HIV-infected patients: a MASTER cohort study

    Two biomarkers, the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), have been shown to be indicative of systemic inflammation and predictive of mortality in general population. We ...

    Elena Raffetti, Francesco Donato, Salvatore Casari, Filippo Castelnuovo, Laura Sighinolfi, Alessandra Bandera, Franco Maggiolo, Nicoletta Ladisa, Massimo di Pietro, Chiara Fornabaio, Simona Digiambenedetto and Eugenia Quiros-Roldan

    BMC Infectious Diseases 2017 17:193

    Published on: 7 March 2017

  7. Research article

    Implementing and sustaining a mobile medical clinic for prenatal care and sexually transmitted infection prevention in rural Mysore, India

    In rural India, mobile medical clinics are useful models for delivering health promotion, education, and care. Mobile medical clinics use fewer providers for larger catchment areas compared to traditional clin...

    Noah Kojima, Karl Krupp, Kavitha Ravi, Savitha Gowda, Poornima Jaykrishna, Caitlyn Leonardson-Placek, Anand Siddhaiah, Claire C. Bristow, Anjali Arun, Jeffrey D. Klausner and Purnima Madhivanan

    BMC Infectious Diseases 2017 17:189

    Published on: 6 March 2017

  8. Research article

    Predictors and incidence of sexually transmitted Hepatitis C virus infection in HIV positive men who have sex with men

    Sexual transmission of Hepatitis C virus (HCV) in men who have sex with men (MSM) and its interaction with HIV status, sexually transmitted infections and sexual behaviour is poorly understood. We assessed the...

    Nicholas A. Medland, Eric P. F. Chow, Catriona S. Bradshaw, Timothy H. R. Read, Joseph J. Sasadeusz and Christopher K. Fairley

    BMC Infectious Diseases 2017 17:185

    Published on: 2 March 2017

  9. Case report

    Reactivation of occult HBV infection in an HIV/HCV Co-infected patient successfully treated with sofosbuvir/ledipasvir: a case report and review of the literature

    Reactivation of occult or inactive Hepatitis B virus (HBV) infection during immunosuppressant treatments is well known and widely described in literature. The same observation has been made in Hepatitis C (HCV...

    Gabriele Fabbri, Ilaria Mastrorosa, Alessandra Vergori, Valentina Mazzotta, Carmela Pinnetti, Susanna Grisetti, Mauro Zaccarelli, Adriana Ammassari and Andrea Antinori

    BMC Infectious Diseases 2017 17:182

    Published on: 1 March 2017

  10. Research article

    The importance of registration of sexual orientation and recognition of indicator conditions for an adequate HIV risk-assessment

    HIV testing among risk groups and guided by HIV indicator conditions (IC) is widely recommended by European guidelines. In this study we investigated how these strategies are used by general practitioners (GP)...

    Ivo K. Joore, Suzanne E. Geerlings, Kees Brinkman, Jan E. A. M. van Bergen and Jan M. Prins

    BMC Infectious Diseases 2017 17:178

    Published on: 28 February 2017

  11. Research article

    Changes in mortality rates and causes of death in a population-based cohort of persons living with and without HIV from 1996 to 2012

    Non-HIV/AIDS-related diseases are gaining prominence as important causes of morbidity and mortality among people living with HIV. The purpose of this study was to characterize and compare changes over time in ...

    Oghenowede Eyawo, Conrado Franco-Villalobos, Mark W. Hull, Adriana Nohpal, Hasina Samji, Paul Sereda, Viviane D. Lima, Jeannie Shoveller, David Moore, Julio S. G. Montaner and Robert S. Hogg

    BMC Infectious Diseases 2017 17:174

    Published on: 27 February 2017

  12. Research article

    The virological durability of first-line ART among HIV-positive adult patients in resource limited settings without virological monitoring: a retrospective analysis of DART trial data

    Few low-income countries have virological monitoring widely available. We estimated the virological durability of first-line antiretroviral therapy (ART) after five years of follow-up among adult Ugandan and Z...

    David I. Dolling, Ruth L. Goodall, Michael Chirara, James Hakim, Peter Nkurunziza, Paula Munderi, David Eram, Dinah Tumukunde, Moira J. Spyer, Charles F. Gilks, Pontiano Kaleebu, David T. Dunn and Deenan Pillay

    BMC Infectious Diseases 2017 17:160

    Published on: 21 February 2017

  13. Research article

    UK national clinical audit: management of pregnancies in women with HIV

    The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to reduce risk has been developed. This project aims to r...

    S. Raffe, H. Curtis, P. Tookey, H. Peters, A. Freedman and Y. Gilleece

    BMC Infectious Diseases 2017 17:158

    Published on: 20 February 2017

  14. Research article

    Prevalence of Human Immunodeficiency Virus and associated factors among Visceral Leishmaniasis infected patients in Northwest Ethiopia: a facility based cross-sectional study

    Visceral Leishmaniasis coinfection with HIV/AIDS has emerged as a series of disease pattern. It most often results in unfavorable responses to treatment, frequent relapses, and deaths. Scarce data is available...

    Mekuriaw Alemayehu, Mamo Wubshet, Nebiyu Mesfin and Abebaw Gebayehu

    BMC Infectious Diseases 2017 17:152

    Published on: 17 February 2017

  15. Research article

    Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era

    HIV+ patients on highly active antiretroviral therapy (HAART) with suppressed viral loads have a low incidence of HIV-associated dementia, but increased prevalence of milder forms of HIV-associated neurocognit...

    Isaac H. Solomon, Umberto De Girolami, Sukrutha Chettimada, Vikas Misra, Elyse J. Singer and Dana Gabuzda

    BMC Infectious Diseases 2017 17:151

    Published on: 17 February 2017

  16. Research article

    Survival of people living with HIV who defaulted from tuberculosis treatment in a cohort, Recife, Brazil

    Tuberculosis is a serious public health problem worldwide. It is the leading cause of death amongst people living with HIV, and default from tuberculosis (TB) treatment in people living with HIV increases the ...

    R Cunha, M Maruza, UR Montarroyos, I Coimbra, D de B Miranda-Filho, M de F Albuquerque, HR Lacerda and RAA Ximenes

    BMC Infectious Diseases 2017 17:137

    Published on: 10 February 2017

  17. Research article

    Successful TB treatment outcome and its associated factors among TB/HIV co-infected patients attending Gondar University Referral Hospital, Northwest Ethiopia: an institution based cross-sectional study

    Tuberculosis/Human immunodeficiency virus (TB/HIV) co-infection is bidirectional and synergistic which mainly affects interventions that have been taken on the area. Tb patients co-infected with HIV have poore...

    Yenework Sinshaw, Shitaye Alemu, Abel Fekadu and Mucheye Gizachew

    BMC Infectious Diseases 2017 17:132

    Published on: 8 February 2017

  18. Research article

    Is it still worthwhile to perform quarterly cd4+ t lymphocyte cell counts on hiv-1 infected stable patients?

    In the last 20 years routine T CD4+ lymphocyte (CD4+) cell count has proved to be a key factor to determine the stage of HIV infection and start or discontinue of prophylaxis for opportunistic infections. Howe...

    Antonio Di Biagio, Marta Ameri, Davide Sirello, Giovanni Cenderello, Enrico Di Bella, Lucia Taramasso, Barbara Giannini, Mauro Giacomini, Claudio Viscoli, Giovanni Cassola and Marcello Montefiori

    BMC Infectious Diseases 2017 17:127

    Published on: 6 February 2017

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