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Significance of a reduction in HCV RNA levels at 4 and 12 weeks in patients infected with HCV genotype 1b for the prediction of the outcome of combination therapy with peginterferon and ribavirin

  • Hidenori Toyoda1,
  • Takashi Kumada1Email author,
  • Noritomo Shimada2,
  • Koichi Takaguchi3,
  • Tatsuya Ide4,
  • Michio Sata4,
  • Hiroyuki Ginba5,
  • Kazuhiro Matsuyama5 and
  • Namiki Izumi6
BMC Infectious Diseases201212:324

DOI: 10.1186/1471-2334-12-324

Received: 2 August 2012

Accepted: 17 November 2012

Published: 27 November 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
2 Aug 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
29 Aug 2012 Reviewed Reviewer Report - Norio Akuta
31 Aug 2012 Reviewed Reviewer Report - Akihito Tsubota
26 Sep 2012 Author responded Author comments - Hidenori Toyoda
Resubmission - Version 3
26 Sep 2012 Submitted Manuscript version 3
16 Oct 2012 Author responded Author comments - Hidenori Toyoda
Resubmission - Version 4
16 Oct 2012 Submitted Manuscript version 4
26 Oct 2012 Author responded Author comments - Hidenori Toyoda
Resubmission - Version 5
26 Oct 2012 Submitted Manuscript version 5
Publishing
17 Nov 2012 Editorially accepted
27 Nov 2012 Article published 10.1186/1471-2334-12-324

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Gastroenterology, Ogaki Municipal Hospital
(2)
Division of Gastroenterology and Hepatology, Shinmatsudo Central General Hospital
(3)
Department of Internal Medicine, Kagawa Prefectural Central Hospital
(4)
Department of Digestive Disease Information and Research, Kurume University School of Medicine
(5)
Department of Life Cycle Management, Roche Diagnostics Japan K.K
(6)
Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital

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