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Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial

  • Andrew Duncan Steele1, 2Email author,
  • Kathleen M Neuzil1,
  • Nigel A Cunliffe3,
  • Shabir A Madhi4, 5,
  • Pieter Bos6,
  • Bagrey Ngwira7,
  • Desiree Witte3, 7,
  • Stacy Todd3,
  • Cheryl Louw8,
  • Mari Kirsten9,
  • Sanet Aspinall10,
  • Leen Jan Van Doorn11,
  • Alain Bouckenooghe12, 13,
  • Pemmaraju V Suryakiran13 and
  • Htay Htay Han13
BMC Infectious Diseases201212:213

DOI: 10.1186/1471-2334-12-213

Received: 28 December 2011

Accepted: 22 August 2012

Published: 13 September 2012

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
28 Dec 2011 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
26 Jan 2012 Reviewed Reviewer Report - Miguel O'Ryan
25 Mar 2012 Reviewed Reviewer Report - Alberto Tozzi
19 Jun 2012 Author responded Author comments - Andrew Duncan Steele
Resubmission - Version 3
19 Jun 2012 Submitted Manuscript version 3
10 Jul 2012 Reviewed Reviewer Report - Alberto Tozzi
Resubmission - Version 4
Submitted Manuscript version 4
22 Aug 2012 Editorially accepted
13 Sep 2012 Article published 10.1186/1471-2334-12-213

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Rotavirus Vaccine Program, PATH
Initiative for Vaccine Research, WHO
Department of Clinical Infection, Microbiology & Immunology, Institute of Infection and Global Health, University of Liverpool
National Institute for Communicable Diseases: a division of National Health Laboratory Services
Department of Science and Technology National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand
MRC Diarrhoeal Pathogens Research Unit, University of Limpopo
Department of Community Health, College of Medicine
Madibeng Centre for Research
Department of Paediatric Surgery, University of Pretoria
Synexus Clinical Research SA/Rota Consortium
DDL Diagnostic Laboratory
Sanofi Pasteur
GSK Biologicals